Stream ‘Grey’s Anatomy’ Season 22 Episode 5 Live on November 6

The long-running medical drama Grey’s Anatomy returns for its 22nd season with a new episode titled “Sometimes I Feel Like a Motherless Child.” The episode is set to air live on November 6, 2025, at 22:00 (10 p.m.) on ABC and will explore the challenges faced by its characters following a shocking death in the season premiere.

In this episode, character Jo grapples with a difficult situation involving a pregnant mother, while her colleagues Jules and Blue manage their own complex case with a patient suffering from diabetes. The series, originally created by Shonda Rhimes, features Ellen Pompeo in the iconic role of Meredith Grey, drawing viewers into the emotional and medical turmoil of life at Grey Sloan Memorial Hospital.

How to Watch Live Without Cable

For those looking to catch the episode live, options include streaming services like DirecTV and Fubo TV, both of which offer free trials. These platforms allow viewers to watch Grey’s Anatomy and other ABC programming as it airs. The episode is expected to conclude around 23:00 (11 p.m.), after which local programming will follow.

If viewers wish to record the episode or watch it on-demand, they can also consider platforms like Sling TV, which offers extensive customization options, although it currently does not provide a free trial. Another option is Hulu, which will carry the series for on-demand viewing following its initial broadcast.

Accessing the Show from Outside the USA

International viewers can still access Grey’s Anatomy by using a Virtual Private Network (VPN) to sign up for services based in the United States. Recommended VPNs include ExpressVPN and NordVPN, both of which offer significant discounts and a money-back guarantee within the first 30 days.

With a rich history and ongoing character development, Grey’s Anatomy continues to captivate audiences. Viewers eagerly anticipate how the series will unfold, especially in light of the emotional arcs explored in the latest episode.